6-letter words with N as the 2nd letter and S as the 4th letter

The pattern is _ N _ S _ _: N holds the second spot and S the fourth. UNISON and UNISEX are familiar examples; several other matches are specialist or uncommon words. Only two entries rank among the top 25,000 English words by frequency, so this narrow clue has a short everyday core surrounded by less familiar options.

Pattern facts at a glance

• There are 18 matches across the tournament dictionaries counted here.
• UNISEX leads the Scrabble scores at 13 points; KNOSPS follows at 12.
• Nine words end in S, while four end in E.
• A is the most common first letter, appearing in five matches.
• Only two matches are common by English word-frequency ranking.

How many of these words end in S?

Nine of the 18 matches finish with S, making that the clearest ending pattern. Four end in E; the remaining five have different final letters. If the last tile is still unknown, UNISON, GNOSIS, and ANGSTS show how often this pattern closes with S.

The starting letters offer another quick filter: five entries begin with A, while E and U each begin three. Dictionary coverage is not identical: ENABLE includes 13 matches, Collins includes 17, and NWL2023 includes 15. Check your game's word list before relying on an unfamiliar option.

Using 6-letter words with N as 2nd and S as 4th

Lock in the known letters first, then test likely first and final letters. UNISON and UNISEX are easier to recognize than GNOSIS or ANISIC, but the less familiar entries still matter when a game accepts them. The key practical limit is frequency: just two matches are common, so a broad vocabulary search will quickly reach obscure terms.

For tile scoring, UNISEX is the standout at 13 points, while KNOSPS reaches 12. Those are raw word scores, not a guarantee of a strong board play; premiums and crossing tiles change the result. Treat the score as a tie-breaker after confirming your game accepts the word.