7-letter words with Y as the 2nd letter and E as the 6th letter

The pattern is _Y___E_: Y sits in the second position, E in the sixth, with four other letters free. The matches range from familiar forms such as typeset and bylines to technical or less common words such as zymogen and lysates. Only one entry is common, so a solved pattern does not guarantee everyday vocabulary.

At a glance: counts, endings, and examples

• Exactly 100 unique words match Y in position two and E in position six.
• Only one match qualifies as common under our frequency measure.
• Collins includes 96 matches; NWL2023 includes 66 and ENABLE includes 59, with overlap between lists.
• G and L are the most frequent first letters, with 11 matches each.
• 65 matches end in S; D accounts for 13 and R for nine.

Which words fit Y in position two and E in position six?

Recognizable examples include gypsies, bygones, typeset, bylines, and zygotes. G and L begin 11 matches apiece, followed by B and M with 10 each. The fixed middle letters do not point to a single opening consonant.

Endings are much less balanced. 65 of the 100 entries finish in S, while 13 end in D and nine in R. Gypsies, pygmies, lynched, and gyrated show several of those endings in familiar forms, though most of the complete set is not everyday vocabulary.

The starting-letter spread is another clue: B and M tie at 10, just behind G and L. If the first square is unknown, test those four openings before assuming the pattern favors one initial.

7-letter words with Y as the 2nd letter and E as the 6th letter

ZYMOMES leads the score list at 23, ahead of ZYMOGEN at 22. KYLIXES, ZYMASES, ZYMOSES, and ZYMITES each score 21; ZYGOTES and HYRAXES reach 20. Rare high-value letters drive these results, so a familiar-looking word does not necessarily top the scoring list.

That scoring edge comes with a vocabulary trade-off: only one match is common, and tournament dictionaries do not include identical sets. Collins covers 96, NWL2023 66, and ENABLE 59; those counts overlap, so the combined total remains 100. Check your game's word list before playing an unfamiliar entry.

For a board clue, lock the second and sixth squares first, then scan endings. S accounts for 65 candidates; every other final letter together accounts for 35. That narrows the search faster than testing opening letters one by one.