6-letter words with Y as the 2nd letter and E as the 6th letter

The pattern is _Y___E: Y sits immediately after the first letter, and E closes every match. B, G, and L each begin six words, while Z begins five. The set is more specialized than its count suggests: just one entry is common by word frequency, although 40 have definitions.

What stands out in this letter pattern

• All 46 matches place Y second and E last.
• BYGONE, MYRTLE, and LYCHEE are recognizable examples.
• B, G, and L each begin six entries; Z begins five.
• ZYMOME scores 22 points, ahead of ZYMASE and ZYMITE at 20 each.
• Only one entry is common by our word-frequency measure.

How many 6-letter words have Y second and E last?

There are 46 matches in Collins, compared with 31 in ENABLE and 31 in NWL2023. That dictionary split matters: a Collins-accepted word can fail in a North American NWL2023 game, so check your game's list before playing an unfamiliar form.

For recognition anchors, try MYRTLE, BYGONE, BYLINE, and LYCHEE. These examples give you very different openings while keeping Y in the second slot and E at the end; they are not a promise that the whole set is familiar.

The first letter offers more sorting power than the last: every answer ends in E, while B, G, and L tie as the most common starters, with six words apiece. Z follows with five.

How can you work this pattern into a play?

Keep the fixed letters as anchors, then test the four open slots against your rack. Start by checking B, G, or L; each leads to six matches, and Z leads to five. This shortlist beats trying every possible first letter.

For points, the obscure end of the set has the edge: ZYMOME scores 22, while ZYMASE and ZYMITE each score 20 before board premiums. The limitation is real: 45 of the 46 matches are not common by this frequency measure, so familiarity alone will not carry your choice.