7-letter words with Y as the 2nd letter and M as the 6th letter

The pattern leaves a compact set, from familiar SYSTEMS to specialist entries such as ZYTHUMS and HYPNUMS. Collins accepts all 15 matches, while ENABLE and NWL2023 each include 9. That dictionary split matters in tournament play: a match for the letter pattern is not automatically valid in every game’s word list.

The pattern at a glance

• 15 tournament-dictionary words put Y second and M sixth.
• SYSTEMS is the only match within the top 25,000 English words by frequency.
• Nine entries end in S; three end in A, two in E, and one in Y.
• H starts 4 matches, more than any other first letter.

Which matches score highest?

ZYTHUMS leads the scoring list at 24 points, well ahead of HYPNUMS at 17. HYGROMA, HYDROMA, and SYNGAMY each score 16, so the unusual-looking options carry the strongest totals.

SYSTEMS is the standout everyday entry, but its score is not among the top results. LYCEUMS and MYELOMA score 14 apiece. For a playable choice, confirm the word in your game’s dictionary: Collins has 15 matches, but the North American list and ENABLE each have 9.

How to narrow the Y-second, M-sixth pattern

Start by fixing the two known tiles: the shape is _Y___M_. Then test likely endings. S is the final letter in 9 of these words, including SYSTEMS, GYPSUMS, and LYCEUMS; A ends HYGROMA, HYDROMA, and MYELOMA.

Only one match is common, which limits this pattern to a specialist vocabulary pool. Changing the second letter to E gives 96 matches; changing the sixth letter to E while keeping Y second gives 100. SYSTEMS is the sole common entry, while ZYTHUMS tops the scores at 24.

H opens four of the 15 words, S opens three, and L and M open two each. B, E, G, and Z open one apiece, so ZYTHUMS is the lone Z entry.