6-letter words with Y as the 2nd letter and S as the 5th letter

This pattern fixes two middle positions, leaving the first and final letters to do much of the work. BYPASS is the clearest everyday example; ZYMASE and ZYGOSE stand out for their scores. The dictionary counts differ too: Collins accepts all 19 matches, while ENABLE and NWL2023 each accept 14.

The pattern at a glance

• Collins lists 19 matches; ENABLE and NWL2023 each list 14.
• Only one match ranks among the top 25,000 English words by frequency.
• ZYMASE scores 20 Scrabble points, ahead of ZYGOSE at 19.
• Seven words end in E, six end in T, and just one ends in S.

6-letter words with Y as the 2nd letter and S as the 5th letter

There are only 19 tournament-dictionary words with Y second and S fifth, making this a narrow pattern. The first letter is C most often, with three matches; B, G, H, L, T, and Z each begin two. No single opening letter covers many options, so use the final slot to narrow your search.

The endings are more concentrated. Seven matches finish in E and six in T, while H and M each close two words. If your final letter is known, check E and T early; an S ending points to BYPASS, the only match that finishes with S.

Familiarity is the main limitation: only one word reaches the common-word frequency cutoff. XYLOSE, GYRASE, and CYMOSE fit the slots, but their meanings are less familiar to many players. Check your game's dictionary when an unfamiliar entry decides the result.

Which matches earn the most Scrabble points?

ZYMASE leads at 20 points, followed by ZYGOSE at 19 and KYBOSH at 18. XYLOSE and TYKISH each score 16. The top scorers use less familiar vocabulary, so a large score alone does not make an entry easy to recall or legal in every game.

For a playable first guess, start with BYPASS rather than memorizing the rare scorers: it is the familiar example in this group and scores 13. The full set of 6-letter words with Y as the 2nd letter and S as the 5th letter averages 13.1 points, but board premiums and your game's rules change the final value.