6-letter words with Y as the 2nd letter and O as the 5th letter

22 words match the pattern. XYSTOI and XYSTOS top the score list at 16 points each; PYTHON and TYCOON are familiar alternatives.

22 wordsTop pick SYMBOLHighest score XYSTOI 16

3 of 22 are everyday words (14%). A mix of familiar words and game-only finds.

With Y in 2nd place, E is the most common 5th letter (73 words). The bar under each letter shows the size of its list.

  • Length
  • 5
  • 6
  • 7
  • 8
  • 9
  • 10
  • 11
  • 12
  • 13
  • 14
  • 15

Best words to play first 22 · most-used first

  • SYMBOL13
  • PYTHON14
  • TYCOON11
  • MYTHOS14
  • TYPHON14
  • SYPHON14
  • HYSSOP14
  • FYNBOS14
  • HYDROS13
  • SYNCOM13
  • CYCLOS13
  • FYLFOT15
  • BYROOM13
  • MYELON11
  • MYTHOI14
  • PYCNON13
  • PYRROL11
  • SYNROC11
  • TYPTOS11
  • XYSTOI16
  • XYSTOS16

Showing the top 21 of 22 words. See every valid word

All valid words 22

A to Z. Includes rare and Collins-only words. Linked tiles open the word's meaning, score and rhymes.

  • BYROOM13
  • CYCLOS13
  • FYLFOT15
  • FYNBOS14
  • GYPPOS14
  • HYDROS13
  • HYSSOP14
  • MYELON11
  • MYTHOI14
  • MYTHOS14
  • PYCNON13
  • PYRROL11
  • PYTHON14
  • SYMBOL13
  • SYNCOM13
  • SYNROC11
  • SYPHON14
  • TYCOON11
  • TYPHON14
  • TYPTOS11
  • XYSTOI16
  • XYSTOS16
Letters by positionIn 32% of these words the 6th letter is S.
1st letter
  1. S18%
  2. T14%
  3. P14%
3rd letter
  1. P18%
  2. C14%
  3. N14%
4th letter
  1. H23%
  2. R14%
  3. T14%
6th letter
  1. S32%
  2. N27%
  3. L9%

Highest-scoring words

Scrabble and Words With Friends points, before board bonuses
Score spreadMost of these words score 14 in Scrabble; XYSTOI tops the list with 16. Scores before board bonuses.
  1. 1111 points: 5 words
  2. 12 points: 0 words
  3. 1313 points: 6 words
  4. 14 points: 8 words
  5. 1515 points: 1 words
  6. 16 points: 2 words
WordScrabbleWords With FriendsDictionaries
XYSTOI1615All three
XYSTOS1615All three
FYLFOT1515All three
PYTHON1414All three
MYTHOS1413All three
TYPHON1414All three
SYPHON1414All three
HYSSOP1413All three
FYNBOS1415Collins · NWL
MYTHOI1413All three
SYMBOL1315All three
HYDROS1311All three

SYMBOL, PYTHON, and TYCOON give you quick ways into this pattern, but the full set includes less familiar vocabulary. The final letter divides these 22 words sharply: seven end in S and six in N. Only three matches rank among the top 25,000 English words, despite familiar anchors such as PYTHON and TYCOON.

Pattern details y 2nd and o 5th letter

  • The final S and N endings cover thirteen candidates.
  • XYSTOI and XYSTOS top the score list at 16 points each; PYTHON and TYCOON are familiar alternatives.
  • Its final letter divides these 22 words sharply: seven end in S and six in N.
  • Only three matches rank among the top 25,000 English words, despite familiar anchors such as PYTHON and TYCOON.

Which words match these positions?

The final letter divides these 22 words sharply: seven end in S and six in N.

S begins four matches, while M, P, and T each begin three.

That gives you a useful second pass after locking Y second and O fifth: test the ending, then narrow by the first tile.

Only three matches rank among the top 25,000 English words, despite familiar anchors such as PYTHON and TYCOON.

XYSTOI, XYSTOS, and FYLFOT push the score table upward, but their specialist feel makes them poor guesses unless the board or rack supports them.

For a board search, confirm the fixed letters first, then use the opening or ending split to eliminate candidates.

The group averages 13.

Playing this exact pattern

The group averages 13.

3 points, yet its top two entries score 16.

PYTHON scores 14, matching MYTHOS, TYPHON, SYPHON, HYSSOP, and FYNBOS.

Don’t assume a recognizable word is the scoring leader; here the rare XYST forms take that spot.

Collins accepts 22 matches, compared with 17 in NWL2023 and 15 in ENABLE.

Check your game's word list before playing an unfamiliar entry.

Dictionary coverage also varies: ENABLE contains fifteen entries, NWL2023 seventeen, and Collins all twenty-two. A printed match count therefore describes the union of those tournament lists.

For a rack search, sort the candidate pool by its ending before evaluating the unusual spellings. SYMBOL and PYTHON make useful recognition points, but XYSTOI and FYLFOT explain why a complete lexicon search reveals more than memory. The repeated O position is only one checkpoint.

Questions people ask

How many matches have O in the fifth position?
There are 22 tournament-list matches with these positions. SYMBOL, PYTHON, and TYCOON are recognizable examples. Seven entries end in S and six in N, giving you a quick way to break a large candidate search into smaller groups.
Why do XYSTOI and XYSTOS lead scoring?
XYSTOI and XYSTOS each score 16 points. FYLFOT follows at 15, while PYTHON and MYTHOS reach 14. The leader pair is less familiar than the alternatives, which is why score and everyday vocabulary diverge here.
Which endings occur most often?
S is the most frequent final letter, with seven matches; N follows with six. The remaining nine words divide among six different endings, so those tail letters narrow candidates quickly once the two fixed positions are known.

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