7-letter words with Y as the 2nd letter and O as the 5th letter

7-letter words with Y as the 2nd letter and O as the 5th letter number 54, led by HYDROXY, which scores 24 points.

54 wordsTop pick SYMBOLSHighest score HYDROXY 24

4 of 54 are everyday words (7%). Mostly rare words: great for Scrabble, tough for daily puzzles.

With Y in 2nd place, I is the most common 5th letter (98 words). The bar under each letter shows the size of its list.

  • Length
  • 5
  • 6
  • 7
  • 8
  • 9
  • 10
  • 11
  • 12
  • 13
  • 14
  • 15

Best words to play first 54 · most-used first

  • SYMBOLS14
  • TYPHOON15
  • CYCLONE14
  • CYCLOPS16
  • TYPHOID16
  • PYTHONS15
  • MYELOMA14
  • HYDROXY24
  • MYELOID13
  • EYESORE10
  • TYCOONS12
  • SYNCOPE14
  • PYRROLE12
  • HYDROID15
  • HYDROUS14
  • SYSTOLE10
  • CYCLOID15
  • HYMNODY19
  • HYDROPS16
  • SYMBOLE14
  • HYALOID14
  • SYPHONS15
  • CYSTOID13
  • EYEHOLE13
  • EYEBOLT12
  • HYGROMA16
  • HYPNOID16
  • HYSSOPS15
  • BYROOMS14
  • BYSSOID13
  • DYEWOOD15
  • DYSLOGY15
  • EYEFOLD14
  • EYEHOOK17
  • EYESOME12
  • FYLFOTS16
  • HYDROMA16
  • HYENOID14
  • HYPNONE15
  • MYELONS12
  • MYOLOGY16
  • MYOSOTE12
  • MYOTOME14
  • PYCNONS14
  • PYGMOID16
  • PYRROLS12
  • SYNCOMS14
  • SYNROCS12

Showing the top 48 of 54 words. See every valid word

All valid words 54

A to Z. Includes rare and Collins-only words. Linked tiles open the word's meaning, score and rhymes.

  • BYROOMS14
  • BYSSOID13
  • CYCLOID15
  • CYCLONE14
  • CYCLOPS16
  • CYSTOID13
  • DYEWOOD15
  • DYSLOGY15
  • EYEBOLT12
  • EYEFOLD14
  • EYEHOLE13
  • EYEHOOK17
  • EYESOME12
  • EYESORE10
  • FYLFOTS16
  • HYALOID14
  • HYDROID15
  • HYDROMA16
  • HYDROPS16
  • HYDROUS14
  • HYDROXY24
  • HYENOID14
  • HYGROMA16
  • HYMNODY19
  • HYPNOID16
  • HYPNONE15
  • HYSSOPS15
  • MYELOID13
  • MYELOMA14
  • MYELONS12
  • MYOLOGY16
  • MYOSOTE12
  • MYOTOME14
  • PYCNONS14
  • PYGMOID16
  • PYRROLE12
  • PYRROLS12
  • PYTHONS15
  • SYMBOLE14
  • SYMBOLS14
  • SYNCOMS14
  • SYNCOPE14
  • SYNROCS12
  • SYNTONE10
  • SYNTONY13
  • SYPHONS15
  • SYSTOLE10
  • TYCOONS12
  • TYPHOID16
  • TYPHONS15
  • TYPHOON15
  • TYPHOSE15
  • TYPHOUS15
  • TYPTOED13
Letters by positionIn 31% of these words the 7th letter is S.
1st letter
  1. H22%
  2. S17%
  3. T13%
3rd letter
  1. E20%
  2. P17%
  3. C9%
4th letter
  1. L17%
  2. R17%
  3. H17%
6th letter
  1. I19%
  2. N19%
  3. L15%
7th letter
  1. S31%
  2. D24%
  3. E24%

Highest-scoring words

Scrabble and Words With Friends points, before board bonuses
Score spreadMost of these words score 14 in Scrabble; HYDROXY tops the list with 24. Scores before board bonuses.
  1. 1010 points: 3 words
  2. 11 points: 0 words
  3. 1212 points: 8 words
  4. 13 points: 6 words
  5. 1414 points: 13 words
  6. 15 points: 12 words
  7. 1616 points: 9 words
  8. 17 points: 1 words
  9. 1818 points: 0 words
  10. 19 points: 1 words
  11. 2020 points: 0 words
  12. 21 points: 0 words
  13. 2222 points: 0 words
  14. 23 points: 0 words
  15. 2424 points: 1 words
WordScrabbleWords With FriendsDictionaries
HYDROXY2421All three
HYMNODY1918All three
EYEHOOK1715All three
CYCLOPS1619All three
TYPHOID1615All three
HYDROPS1615All three
HYGROMA1616Collins only
HYPNOID1616All three
HYDROMA1615Collins only
PYGMOID1618All three
FYLFOTS1616All three
MYOLOGY1617All three

The fixed pattern is _Y__O__, so a clue gives you two anchors before you scan the remaining letters. The 54 matches range from familiar forms such as SYMBOLS and CYCLONE to specialist entries such as HYDROXY and HYDROPS. Four entries meet the common-word cutoff, so expect a narrow pool rather than an everyday vocabulary list.

Quick facts about this letter pattern

  • The pattern returns 54 words across the tournament dictionaries counted here.
  • HYDROXY leads the scoring examples at 24 points, ahead of HYMNODY at 19.
  • H is the most frequent first letter, starting 12 of these words.
  • SYMBOLS, TYPHOON, and CYCLONE are among the more recognizable matches.
  • Only four matches meet the common-word cutoff, so many options are specialized.

7-letter words with Y as the 2nd letter and O as the 5th letter

HYDROXY is the standout scorer at 24 points, while HYMNODY reaches 19 and EYEHOOK scores 17. Those values make the less familiar words worth remembering when a rack has a valuable Y or X; the board layout still determines the final turn score.

The opening letters give you a useful way to narrow the search: H begins 12 matches, S begins nine, and T begins seven. Try those groups first when the first tile is known. HYDROXY, HYDROPS, and HYDROID also show how often this pattern clusters around the HY- start.

  • HYDROXY scores 24 points, the highest tile score among these examples.
  • HYMNODY reaches 19 points; EYEHOOK scores 17.
  • H starts 12 matches, ahead of S with nine and T with seven.

How does this pattern compare with nearby clues?

The second-letter Y is a tight constraint here: changing the fifth letter to N gives 44 matches, while M gives 15. Changing the second letter to A with O still fifth expands the pool to 578. That contrast makes the fixed Y the stronger filter when you are testing possible patterns.

Seven-letter matches also split unevenly by ending: 17 end in S, while 13 end in D and another 13 in E. SYMBOLS and TYPHOONS-like plural forms are easy to spot by their final S, but the list also includes singular endings such as HYDROID. Only four matches are common, so check your game's word list before relying on a rare entry.

  • Changing the fifth letter to N gives 44 matches; M gives 15.
  • With A second and O fifth, the neighboring pattern has 578 matches.
  • S is the most frequent ending at 17; D and E each end 13 words.

Questions people ask

What is the highest-scoring word with Y second and O fifth?
HYDROXY is the top scorer, worth 24 points before any board bonuses. HYMNODY follows at 19, and EYEHOOK scores 17. These are tile values, not guaranteed turn totals; premium squares can change what you earn when you play them.
Are many of these seven-letter words common?
No; only four of the 54 matches meet the common-word cutoff. SYMBOLS and CYCLONE are more familiar examples, while HYDROXY and HYDROPS are more specialized. The pattern is precise, but it does not produce a large everyday vocabulary set.
Do all word-game dictionaries accept the same matches?
No. Collins includes 53 matches, compared with 43 in NWL2023 and 41 in ENABLE. HYDROXY is a useful high-scoring example, but dictionary coverage differs, so check your game's word list before playing less familiar entries.

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