6-letter words with D as the 2nd letter and E as the 6th letter

The pattern is _D___E: D is fixed in the second slot and E closes every match. Nine words begin with A, while only one each begins with E, I, or S. ADVICE, ADVISE, and ADMIRE are recognizable options; several remaining entries are less familiar, so check the word list used by your game.

The D _ _ _ _ E pattern

• All 12 matches appear in at least one of Collins, NWL2023, or ENABLE.
• Nine start with A; the other three start with E, I, and S.
• Five matches rank among common English words by frequency.
• ADJURE scores 14, ahead of ADVICE at 12.

6-letter words with D as 2nd and E as 6th

The fixed ending E does not make this pattern broad: just 12 words match. Change the second letter from D to E and the same six-letter, final-E pattern has 424 matches; change it to O and there are 418. That contrast makes the second-position clue the real filter, not the final E.

Nine of the 12 candidates begin with A, a striking concentration. ADVICE and ADVISE are the easiest pair to mix up: both fit, but the fifth letter changes from C to S. If your first tile is A, keep both in mind until another clue rules one out.

ADJURE is the score leader at 14, while ADVICE scores 12. The J gives ADJURE its edge in the base Scrabble score; a premium square can increase the play’s total, but board placement decides that.

How do you narrow this pattern in a puzzle?

For 6-letter words with D as 2nd and E as 6th, the starting letter is a quick filter: nine candidates begin with A, while E, I, and S each start just one. Five of the 12 are common by frequency, so the set mixes familiar vocabulary with less everyday entries.

Dictionary coverage differs across the tournament lists: Collins includes all 12 matches, NWL2023 includes 10, and ENABLE includes nine. A word accepted in one list may not work in another, so treat these as candidates and check the rules for your game.

The broader comparison is useful when a clue feels too restrictive: keeping the last E but changing the second letter to E gives 424 matches. That makes the D clue the limiting feature. If D is uncertain, test that tile before spending time on rarer possibilities such as ADVENE or SDAINE.