6-letter words with U as the 1st letter and S as the 4th letter

Only 15 tournament-dictionary words fit this six-letter pattern: U opens each word, and S sits in the fourth position. The group is unusually narrow beside nearby patterns, with U-first words using I or E in slot four numbering 100 and 97. Most matches also end in S, but three exceptions finish with D, N, or X.

At a glance: the U-S pattern

• All 15 matches have six letters, start with U, and place S fourth.
• UNISEX leads the score list at 13 points; UKASES scores 10 and UPASES scores 8.
• Twelve matches end in S; UNUSED, UNISON, and UNISEX end in D, N, and X.
• Just 2 entries meet the common-word frequency cutoff, so expect many less familiar options.

Which words fit the U-S pattern?

UNISEX is easy to verify by its shape: U-N-I-S-E-X puts S in slot four and ends in X. UNISON has the same first four letters but ends in N, while UNUSED ends in D. Check the final tile to distinguish these three candidates.

For a higher score, UNISEX leads at 13 points, ahead of UKASES at 10 and UPASES at 8. The latter two are less familiar choices.

6-letter words with U as the 1st letter and S as the 4th letter

Collins includes all 15 matches, while NWL2023 and ENABLE each include 7. That difference matters in tournament play: a word accepted in one list may not be accepted in another, so check your game's lexicon before playing an unfamiliar entry. Other first letters give far bigger pools: P with S fourth has 127 words and C has 104, so U is a thin slot for this clue.

Only 2 matches meet the common-word frequency cutoff, and the group averages 6.9 points. UNISON and UNUSED are recognizable examples. Treat the full set as a pattern-matching aid, not a list of equally familiar words.