Menu
Find words

14-letter words with Z as the 2nd letter

14-letter words with Z as the 2nd letter number just one: AZIDOTHYMIDINE, included in ENABLE, Collins, and NWL2023.

1 wordTop pick AZIDOTHYMIDINEHighest score AZIDOTHYMIDINE 33

E is the most common 2nd letter in 14-letter words (1,611 words); Z is the rarest (1). The bar under each letter shows the size of its list.

Best words to play first 1 · most-used first

  • AZIDOTHYMIDINE33
All valid words 1

A to Z. Includes rare and Collins-only words. Linked tiles open the word's meaning, score and rhymes.

  • AZIDOTHYMIDINE33

Highest-scoring words

Scrabble and Words With Friends points, before board bonuses
WordScrabbleWords With FriendsDictionaries
AZIDOTHYMIDINE3333All three

One unusual fact defines this pattern: the entire 14-letter set is AZIDOTHYMIDINE. Z sits immediately after the opening A, and the word is the only match across the tournament lists represented here. That makes this a precision clue rather than a page for browsing many interchangeable answers.

14-letter words with Z as the 2nd letter at a glance

  • AZIDOTHYMIDINE is the sole match, with A first, Z second, and E last.
  • ENABLE, Collins, and NWL2023 each include the word.
  • Its recorded average and highest score are both 33 points.
  • The common-word count is zero; this is a singleton, not a broad vocabulary pool.

Why is Z so scarce in this position?

Z is the second letter in just one 14-letter entry, while E occupies that position in 1,611. The contrast is sharp even among long words: 14-letter words with X second number 92, while Z has a single match. For this exact length-and-position filter, Z is the bottleneck.

The lone answer starts with A, so the pattern is AZ followed by the remaining letters of AZIDOTHYMIDINE. If your clue already fixes the second tile as Z, keep the full length in view; a shorter AZ word will not satisfy this filter.

How to use 14-letter words with Z as the 2nd letter

Treat AZIDOTHYMIDINE as a specific fit, not a flexible bank of options. The list has no alternate match to swap in if another crossing letter rules it out, so confirm the A at the start and E at the end before committing.

The word scores 33 points, making it the top scorer here by default as well as the only entry. That score makes the unusual spelling worth checking on a tile rack, but the zero common-word count is a reminder that it is not everyday vocabulary. Check your game's word list before playing it; the matching entry appears in all three named tournament dictionaries.

Questions people ask

Is AZIDOTHYMIDINE the only 14-letter word with Z second?
Yes. AZIDOTHYMIDINE is the only 14-letter match with Z in position two in the tournament dictionaries represented here. ENABLE, Collins, and NWL2023 all include it, so the match is not restricted to just one of those lists. The word begins with A and ends with E.
What is the highest-scoring 14-letter word with Z second?
AZIDOTHYMIDINE is the highest-scoring match, at 33 points. It is also the only word in this pattern, so there is no second entry to compare against. Check the scoring rules and board conditions for your game before treating that figure as your final play score.
Are any common words 14 letters long with Z as the second letter?
No common words match this pattern. AZIDOTHYMIDINE is the sole entry, and the common-word count for the set is zero. The clue is therefore much more likely to point to a specialized vocabulary item than to a familiar everyday word.

Keep going