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13-letter words with Z as the 2nd letter

13-letter words with Z as the 2nd letter: exactly one tournament-dictionary entry fits, AZATHIOPRINES, scoring 27 points.

1 wordTop pick AZATHIOPRINESHighest score AZATHIOPRINES 27

E is the most common 2nd letter in 13-letter words (2,456 words); Z is the rarest (1). The bar under each letter shows the size of its list.

Best words to play first 1 · most-used first

  • AZATHIOPRINES27
All valid words 1

A to Z. Includes rare and Collins-only words. Linked tiles open the word's meaning, score and rhymes.

  • AZATHIOPRINES27

Highest-scoring words

Scrabble and Words With Friends points, before board bonuses
WordScrabbleWords With FriendsDictionaries
AZATHIOPRINES2728All three

This pattern is exceptionally narrow: the complete 13-letter set contains just one word. AZATHIOPRINES appears in ENABLE, Collins, and NWL2023, but it is not classed as common. Treat the clue as a precise spelling problem rather than a prompt to brainstorm familiar vocabulary; the unusual letter sequence does most of the work.

The single match at a glance

  • Exactly one 13-letter entry has Z in position two: AZATHIOPRINES.
  • AZATHIOPRINES appears in ENABLE, Collins, and NWL2023.
  • Its 27-point score is the highest score in this one-word set.
  • The common-word count is zero, so expect an obscure entry rather than everyday vocabulary.

Why are there so few 13-letter words with Z second?

Only one word matches this exact length and position, while the neighboring second-letter patterns are much broader. For comparison, 13-letter words with X second number 184, and those with Y second number 481. Those figures make Z an extreme outlier among the same-length patterns.

Length changes the picture too: the 12-letter Z-second set has eight entries, and the 14-letter set has one. The 13-letter result is therefore not part of a steady rise or fall; it is a solitary match between two small neighboring sets.

That contrast gives you a practical clue-solving rule: lock in the length and letter position before searching. Broadening the search to every 13-letter word or every Z pattern would add noise without producing another match.

How to check 13-letter words with Z as the 2nd letter

Start by confirming the pattern: AZATHIOPRINES has A first and Z second, then continues for a total of 13 letters. If your crossing letters disagree with that opening, this sole match cannot fit the board. The unusual spelling makes a position-by-position check safer than relying on a quick visual scan.

Its 27-point score is striking, but the length and placement of the letters still matter on a board. A high base score does not guarantee a strong play if the word cannot connect to existing tiles or reach a premium square. Check your game's accepted lexicon before playing; a tournament listing does not guarantee every game uses the same word list.

For nearby searches, compare other 13-letter second-letter patterns or keep Z fixed and change the length. The 12-letter and 14-letter sets each remain small, while the X- and Y-second 13-letter sets offer much larger alternatives.

Questions people ask

What 13-letter word has Z as its second letter?
AZATHIOPRINES is the only 13-letter match with Z in the second position. It appears in ENABLE, Collins, and NWL2023. Check each letter against your clue, since this uncommon spelling leaves little room for a near-match.
How many 13-letter words have Z as the second letter?
There is exactly one match: AZATHIOPRINES. The count is much smaller than for the neighboring X- and Y-second patterns, which have 184 and 481 entries respectively. That makes Z a particularly restrictive clue at this length.
How many points is AZATHIOPRINES worth?
AZATHIOPRINES scores 27 points by its letter values before any board bonuses. That is the highest score in this set, which contains no other matching word. Placement still determines the final play value, so account for connecting tiles and premium squares.

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