5-letter words with S as the 2nd letter and E as the 5th letter

5-letter words with S as the 2nd letter and E as the 5th letter: 11 matches, from familiar ISSUE to the 14-point USQUE.

11 wordsTop pick ISSUEHighest score USQUE 14

3 of 11 are everyday words (27%). A mix of familiar words and game-only finds.

  • 5th letter
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

With S in 2nd place, S is the most common 5th letter (14 words). The bar under each letter shows the size of its list.

  • Length
  • 5
  • 6
  • 7
  • 8
  • 9
  • 10
  • 11
  • 12
  • 13
  • 14
  • 15

Best words to play first 11 · most-used first

All valid words 11

A to Z. Includes rare and Collins-only words. Linked tiles open the word's meaning, score and rhymes.

Highest-scoring words

Scrabble and Words With Friends points, before board bonuses
WordScrabbleWords With FriendsDictionaries
USQUE1416All three
YSAME1010Collins only
PSOAE78All three
ASIDE66All three
USAGE68All three
TSADE66All three
ISSUE56All three
ISNAE56Collins only
ISTLE56All three
ESILE56Collins only
USURE57Collins only

The pattern is _S__E: S must sit immediately after the first letter, and E closes the word. That leaves a compact set of 11 tournament-dictionary entries, with a sharp split between familiar words such as ASIDE and USAGE and less familiar options such as PSOAE. Every match ends in E, so a confirmed final letter narrows the search further.

The _S__E pattern at a glance

  • There are 11 five-letter matches, and every one ends with E.
  • Only 3 matches fall within the common-word group: a small everyday subset.
  • Collins includes all 11; ENABLE and NWL2023 include 7 each.
  • USQUE leads the score list at 14 points; YSAME follows at 10.
  • Three matches appear in the Wordle answer list, while all 11 are allowed guesses.

Which 5-letter words have S second and E fifth?

The full set is ASIDE, ESILE, ISNAE, ISSUE, ISTLE, PSOAE, TSADE, USAGE, USQUE, USURE, and YSAME. ISSUE, ASIDE, and USAGE are the most recognizable at a glance; several others are less likely to come to mind during a timed puzzle.

Use the fixed letters before guessing: keep S in slot two and E in slot five, then test the open positions against your clues. ISSUE and USAGE share the same second and final letters but differ in the middle, while ASIDE starts with A. The narrow pattern helps, but it does not make every match equally familiar.

How should you use these matches in a game?

For Wordle, the pattern has 3 answer-list matches and 11 allowed guesses. Treat the answer overlap as a short shortlist, not a promise that a particular familiar-looking word is the solution; the matching set also contains uncommon entries.

For Scrabble scoring, USQUE is the standout at 14 points, while YSAME scores 10. Those totals make USQUE the scoring leader, not the easiest play to spot.

Dictionary coverage also differs: Collins has all 11 words, compared with 7 in each of ENABLE and NWL2023. Check your game's word list before relying on the less familiar entries.

Questions people ask

How many five-letter words match _S__E?
There are 11 tournament-dictionary words matching _S__E. Every match has S in the second position and E at the end, including familiar options such as ISSUE and ASIDE as well as less familiar words like USQUE.
Which _S__E word has the highest Scrabble score?
USQUE is the highest scorer in this set at 14 points. YSAME is next at 10, so USQUE has a four-point lead before any board premiums or other play-specific effects.
Are all 11 words accepted in every word-game dictionary?
No. Collins lists all 11 matches, while ENABLE and NWL2023 list 7 each. That difference matters when you play across dictionaries, especially with less familiar entries such as PSOAE or USURE; check the word list used by your game.

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