7-letter words with P as the 2nd letter and U as the 6th letter

The pattern fixes two positions but leaves the first, third, fourth, fifth, and final letters open. That still produces a short set: only 14 words qualify, and just two meet our frequency threshold for common words. Examples range from OPTIMUM and APPLAUD to less familiar entries such as EPHEBUS and APERCUS.

7-letter words with P second and U sixth

• Fourteen entries match: P sits second and U sits sixth.
• Only two qualify as common by our frequency measure.
• Five begin with S, while six end with S.
• Collins accepts all 14; ENABLE and NWL2023 each include 10.

Which matching words score the most?

EPHEBUS leads the Scrabble scores at 14 points. OPTIMUM follows at 13, while APPLAUD, SPEEDUP, SPODIUM, and UPVALUE each score 12. Those point totals are before any board bonuses, so a premium square can change the final result.

For more familiar starting points, try OPTIMUM, APPLAUD, or OPOSSUM. The less everyday options include APERCUS, APODOUS, and SPUMOUS. Treat the fixed letters as a filter, not proof that every result will be familiar or accepted in your game.

How should you use the fixed letters?

Lock P into position two and U into position six before testing the remaining spaces. The opening letter gives a useful next filter: five matches start with S, compared with three each starting with A or O, two with E, and one with U. The remaining starts are distributed across E and U: EPERDUE and UPVALUE show how sparse those opening groups are.

The final letter offers another strong clue: six matches end in S, more than any other ending. That does not mean every S-ending answer is an obvious word; several entries are uncommon. The 7-letter words with P second and U sixth are a narrow pattern, so check your game's word list before playing a doubtful entry.