6-letter words with M as the 2nd letter and I as the 5th letter

M sits in slot two and I in slot five, leaving four positions open. The remaining letters make a short, unusual group, not a list of everyday vocabulary. E and A lead as openings, while C is the most frequent ending; only one entry ranks as common by word frequency.

The M-second, I-fifth pattern at a glance

• The pattern has 22 six-letter matches across the tournament dictionaries counted here.
• EMOJIS leads the scores at 15 points; AMYLIC follows at 13.
• E opens 8 words and A opens 7, making them the dominant first letters.
• C closes 7 words, ahead of S with 5.

Which letters open and close these words?

E and A account for 15 of the 22 openings together. That leaves just seven words beginning with I, U, S, or T; IMPAIR is a recognizable example from the I group. When solving, test E and A before spending guesses on the less frequent starts.

C is the leading ending, appearing in 7 matches, while S appears in 5. Other endings are more scattered: L and N each finish 3 words. EMOJIS is a scoring standout and a clear example of the S ending, while AMEBIC shows the frequent C ending.

Using 6-letter words with M second and I fifth

The dictionary counts differ: Collins includes 20 matches, NWL2023 includes 16, and ENABLE includes 13. A word accepted in one list may not appear in another, so check your game's word list before relying on an unfamiliar entry. This matters especially for a pattern with so few common words.

EMOJIS scores 15 points, ahead of AMYLIC at 13; SMOKIE and AMEBIC each score 12. The average score is 10.1, but score alone does not make an entry playable in every dictionary. Treat the less familiar words as candidates to verify, not automatic plays.