6-letter words with L as the 4th letter and U as the 5th letter

The fixed pattern is _ _ _ L U _, so the fifth letter is set while the final letter stays open. The 45 matches span eight ending letters: S leads with 14, followed by M with 13 and X with five. Familiar choices are scarce: only three entries fall among the 25,000 most frequent English words.

6-letter words with L fourth and U fifth at a glance

• 45 tournament-dictionary words fit the _ _ _ L U _ pattern.
• ASYLUM, STYLUS, and INFLUX are recognizable examples.
• Fourteen end in S, and 13 end in M.
• EFFLUX and AFFLUX tie for the highest score at 19.
• Only three matches meet the common-word cutoff.

Which final letters appear most often?

S is the leading final letter, with 14 matches; M follows with 13, and X has five. Together, S and M account for 27 of the 45 words. CALLUS and PHYLUM show the two leading endings, while INFLUX and REFLUX illustrate the X group.

The remaining endings are much less common: E and P have three matches each, K and T have two each, and B appears once. If your clue leaves the last letter unknown, testing S or M first covers more of this pattern than testing any other ending overall.

Which matches score highest, and do dictionaries agree?

EFFLUX and AFFLUX lead the score list at 19 points each. INFLUX, REFLUX, PHYLUM, HALLUX, and MUKLUK each score 16. The X-ending words stand out for scoring: three of those five X matches appear among the top scores.

Dictionary coverage differs: 44 matches appear in Collins, 32 in NWL2023, and 28 in ENABLE. The total counts words found in at least one of these tournament lists, so check your game's word list before playing an unfamiliar entry. For a nearby pattern, switching the fifth letter to T gives 40 matches; switching L to O gives 120.